Custom-made TAP service
In addition to the off-the-shelf TAPs, FibroTx is offering development of customized TAPs to meet clients needs. For this, FibroTx will develop optimal TAP capture antibody micro-arrays, as well as optimal protocols for biomarker capture and detection from skin. This is to secure the highest specificity and sensitivity, as well as for finding the optimal dynamic range needed for skin biomarker measurements in the client’s study.
Biomarkers for the custom-made TAP can be either chosen from the list below or suggested by the client. The layout and number of different biomarkers on TAP can be adjusted to meet specific needs of the client.
Biomarkers that have been tested so far:
|IL-1α||Interleukin-1 alpha||IL-1RA||Interleukin-1 receptor antagonist protein|
|hBD-1||Beta-defensin 1||CXCL-2||C-X-C motif chemokine 2|
|TSLP||Thymic stromal lymphopoietin||VEGF||Vascular endothelial growth factor|
|CXCL-1||Growth-regulated alpha protein||CCL-2||C-C motif chemokine 2|
|TNF-α||Tumor necrosis factor||IL-4||Interleukin-4|
|CXCL-3||C-X-C motif chemokine 3||hBD-4||Beta-defensin 104|
|TL-1A||Tumor necrosis factor ligand superfamily member 15||IL-18||Interleukin-18|
|Keratin-16||Keratin, type I cytoskeletal 16||CXCL-12||Stromal cell-derived factor 1|
|CCL-27||C-C motif chemokine 27|