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Custom-made TAP service

 

In addition to the off-the-shelf TAPs, FibroTx is offering development of customized TAPs to meet clients needs. For this, FibroTx will develop optimal TAP capture antibody micro-arrays, as well as optimal protocols for biomarker capture and detection from skin. This is to secure the highest specificity and sensitivity, as well as for finding the optimal dynamic range needed for skin biomarker measurements in the client’s study.

Biomarkers for the custom-made TAP can be either chosen from the list below or suggested by the client. The layout and number of different biomarkers on TAP can be adjusted to meet specific needs of the client.

 

Biomarkers that have been tested so far:

IL-1α Interleukin-1 alpha IL-1RA Interleukin-1 receptor antagonist protein
hBD-1 Beta-defensin 1 CXCL-2 C-X-C motif chemokine 2
PI3 Elafin CRP C-reactive protein
hBD-2 Beta-defensin 4A IL-8 Interleukin-8
TSLP Thymic stromal lymphopoietin VEGF Vascular endothelial growth factor
CXCL-1 Growth-regulated alpha protein CCL-2 C-C motif chemokine 2
TNF-α Tumor necrosis factor IL-4 Interleukin-4
CXCL-3 C-X-C motif chemokine 3 hBD-4 Beta-defensin 104
TL-1A Tumor necrosis factor ligand superfamily member 15 IL-18 Interleukin-18
Keratin-16 Keratin, type I cytoskeletal 16 CXCL-12 Stromal cell-derived factor 1
CCL-27 C-C motif chemokine 27